Online sales in 2022 that took place on B2B marketplaces grew to $112 billion. That's double 2021's sales, according to estimates and analysis in the forthcoming B2B Ecommerce Market report. There are currently more than 400 B2B marketplaces in the U.S., up from about 100 just a few years ago.

As 2022 ended, B2B marketplaces in the United States were on an accelerated growth rate. And though that acceleration was slower than in 2021, B2B marketplaces are still the fastest-growing ecommerce sales channel and like to remain so for at least the foreseeable future.

In 2022, the online sales that took place on B2B marketplaces grew to $112 billion. That’s up 100% from $56 billion on 2021, based on estimates from data and analysis contained in the forthcoming 2023 B2B Ecommerce Market report from Digital Commerce 360.

There are currently more than 400 B2B marketplaces in the U.S., and those general business and vertical industry marketplaces come in several models. And more new marketplaces are on the way, along with the expansion of existing ones.

In health care, a systems integrator for digital health care applications has formed a B2B marketplace aimed at hospitals and health systems.

The aim of the new Avia Marketplace platform,, is to give health providers and health care technology vendors a marketplace to find and purchase new digital systems for hospital functions such as:

  • Remote patient modeling
  • Billing and payment
  • Prior authorization
  • Virtual visits

B2B marketplaces have grown since 2015 and now have had a combined enterprise value of $214 billion, says

After the first wave in the early 2000s, B2B marketplaces have expanded to a larger portion of their industry value chain,” says “This expansion occurred due to advances in three main high-level functions: supply and demand aggregators, procurement tools and financing solutions.”

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